Z Factor Ltd, a Cambridge-based drug development company spun out of the University of Cambridge, announced that the first human volunteer was dosed today with ZF874, its novel treatment for alpha-1-antitrypsin deficiency (AATD). AATD is a common genetic disorder, affecting around in 1 in 2000 people in Western countries, whereContinue Reading

RICHLAND, WA- The Wishing Star Foundation is a non-profit based out of Spokane that grants the wishes of children ages 3-21 with terminal, life threatening or medically complicated conditions. Friday the non-profit granted the wish of a young Richland girl named Oaklee McBride. Oaklee has Alpha-1 Antitrypsin Deficiency an inherited condition thatContinue Reading

Researchers from the Center for Regenerative Medicine (CReM) have assembled the largest repository of patient derived stem cells (iPSCs) from patients with alpha-1 antitrypsin deficiency (AATD). “Our goal is to get these cells out to other researchers so that they will use them to ultimately help patients with AATD. ToContinue Reading

Alpha-1 Awareness is a charity founded and run by volunteers to help bring awareness of AATD as well as give support to those affected, their families, friends and carers.  We can’t do this alone, and we are so thankful to those who help in our Facebook Group respond to people’sContinue Reading

[Warning: The below contains MAJOR spoilers for Season 16, Episode 15 of Grey’s Anatomy, “Snowblind.”] The blizzard isn’t the only disaster in this Grey’s Anatomy episode—Season 16, Episode 15 Hayes’ patient this week is Elisa, a 6-year-old with alpha-1 antitrypsin deficiency—the same disorder that killed her older sister, one of Alex’s patients. ElisaContinue Reading