The COVID-19 pandemic is a global emergency. Identifying populations who are at risk of severe complications is crucial in developing special measures to prevent or reduce severe illness and mortality in vulnerable patients. Emerging evidence indicates that alpha1-proteinase inhibitor might inhibit infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). α1-AntitrypsinContinue Reading

18th October 2020  Professor Gerry McElvaney (left), the study’s senior author and a consultant in Beaumont Hospital, and Professor Ger Curley (right) stand in front of the RCSI Education and Research Centre in Beaumont Hospital, Dublin.   Scientists have developed, for the first time, a score that can accurately predictContinue Reading

Researchers from the Center for Regenerative Medicine (CReM) have assembled the largest repository of patient derived stem cells (iPSCs) from patients with alpha-1 antitrypsin deficiency (AATD). “Our goal is to get these cells out to other researchers so that they will use them to ultimately help patients with AATD. ToContinue Reading

(Boston)–Using a combination of pluripotent stem cells (cells that can potentially produce any cell or tissue type) and machine learning (artificial intelligence that allows computers to learn automatically), researchers have improved how they generate lung cells. Using this technique, cells can be grown in a laboratory and stored for moreContinue Reading

Shirts with smart technology could be used in place of traditional laboratory equipment to measure lung function, and prove to be particularly useful in respiratory conditions such as asthma, cystic fibrosis, or chronic obstructive pulmonary disease (COPD), new research suggests. The data were discussed in a presentation, titled “Tidal volumes during tasks ofContinue Reading

Ronald G. Crystal, MD, is chair of the department of genetic medicine at Weill Cornell Medical College in New York, where he has worked for 26 years. He is one of the pioneers of gene therapy. After training with W. French Anderson, he led some of the first in vivoContinue Reading