Prof. Dr. Sabina Janciauskiene`s interest in alpha1-antitrypsin began in 1986, with a development of specific monoclonal antibody against alpha1-antitrypsin at the Thermo Fisher Scientific Vilnius (former Fermentas). From 1991 to 2009 she was conducting research at the department of Gastroenterology and Hepatology, at Malmö University hospital. During this time her research group have studied different molecular forms of antitrypsin and was among the first to show that antitrypsin expresses immunomodulatory activities independent on its well-recognized ability to inhibit neutrophil proteases.
Currently Sabina is a head of “Molecular Pulmonology” research group at the Department of Respiratory Medicine, Hannover Medical School, which is also a part of the BREATH cluster of excellence at the German Centre for Lung Research (DZL). The major area of her research is molecular mechanism and biomarkers of acute and chronic inflammatory diseases with a specific focus on protease/anti-protease systems and alpha1-antitrypsin.